Othello's enemy "Othello" character "Othello" home wrecker "O, beware, my lord, of jealousy" spkr. "Othello" provocateur "Othello" conniver "Othello" fellow "Othello" traitor Othello's betrayer Othello's false friend "Othello" schemer Othello's confidant "Othello" conspirator "O, beware, my lord, of jealousy" speaker "Othello" antagonist "Otello" baritone "Othello" role "Othello" villain Othello deceiver "Othello" heavy Othello villain Othello's antagonist "Othello" evildoer Othello's betrayer "Othello" heavy Othello's ensign Othello's ill-wisher "Othello" bad guy Othello's undoer Othello's foe "Othello" antagonist "Othello" plotter Othello adversary Othello foe Othello's adversary "Othello" villain "Otello" bad guy "Othello" role "Othello" antagonist "Othello" villain Othello's tormentor "Othello" baddie "Othello" schemer Othello's ancient "Otello" baritone Othello's "ancient." Othello's villainous ensign. One of Ferrer's roles. Operatic villain. Opera role. Othello's ancient. Operatic role. Othello's ensign. Othello's "friend." "Othello" character. Othello's friend "Othello" man Othello's aide Othello's villainous ensign "Othello" character Operatic and dramatic villain Othello's "consigliere" Othello's perfidious aide Othello's deceiver Othello's antagonist Othello's villainous aide "Othello" heavy Othello's nemesis "Othello" plotter Openings of books like Ulysses: extremely coarse Oxbridge player Oxbridge sportsperson Officiating priests at mosques Of great importance Of global significance Opposite of smash Origin of the Euphrates Opposite of smash One of the bad films produced for Christmas market Obscure Obscure Obstruct the view of. "O tiger's heart wrapp'd in a woman's ___!": Shak. Obscure Online option that turns into "show" when clicked Online option that turns into 'show' when clicked One of a bevy Outtake Outtake One of those on the runway to broadcast with one of those overseas One of those perhaps planning to take off broadcast by one of those overseas On the whole ... or, when read in two parts, what the answer to each starred clue has On the whole ... or, when read in two parts, what the answer to each starred clue has Oldtimers' game One of 39-Across Original 'Hee Haw' airer One of the old Big Three Organization depicted in "Good Night, and Good Luck" One of the major networks Onetime teen heartthrob Efron One of pop's Hanson brothers Onetime teen heartthrob Efron Org. that may say no to drugs Org. that banned ephedra Org. that holds trials Org. that banned candy-flavored cigarettes Org. that tests cosmetics Org. concerned with meds Org. that regulates vaccines Org. requiring milk pasteurization Org. regulating vaccines OTC drug overseer OTC drug regulator Org. that banned cyclamates in 1970 Org. that okays new medicines Org. that banned ephedra Org. overseeing nutrition labeling Org. that may request a recall Org. whose approval is much sought Org. that gives approvals Org. that may call for a recall Occasional medicine dropper?: Abbr. Org. overseeing trials Org. that approves new pharmaceuticals Org. that regulates tobacco products O.T.C. O.K.'er Org. that will study cell-phone safety Org. that's a real medicine dropper Org. that approves medications Org. approving new medicines Org. approving medicines Org. that may say no to drugs Org. that banned ephedra Org. that approves things Org. that may say "no" to drugs Org. that may say no to drugs Org. that includes the Center for Tobacco Products Org. whose approval is often sought Org. that holds trials Org. that regulates dietary supplements O.T.C. O.K.'er Org. that includes the Center for Tobacco Products Org. whose approval is often sought Org. that may say no to drugs Org. that regulates dietary supplements Org. approving new medicines Org. that OKs medications Org. approving medicines Org. that may say no to drugs Org. that approves things Org. that approves medicines OTC med regulator Org. requiring milk pasteurization Org. regulating vaccines OTC drug regulator OTC drug regulator OTC drug overseer OTC drug overseer Org. that holds trials OTC drug agency OTC drug agency Org. that tests cosmetics Org. that tests cosmetics OTC medication monitor Org. that approves medications Org. that grants emergency use authorizations Operation Warp Speed org Org. that grants emergency use authorization Order to a platoon "Oh, were it not so" 'Oh, were it not so!' 'Oh, were it not so' 'Oh, what a world!' 'O woe!' "Oh, dear me!" "Oh, me!" "Oh well!" "Oh, poor me" "Oh woe!" "Oh, were it not so!" "Oh, dear!" 'Oh, woe!' Old-school lament Oh dear Oh dear! 'Oh, what a terrible pity!' 'Oh, dear!' Oh dear "Oh well," of long ago 'Oh, what a shame!' Old poet's cry of grief 'Oh dear!' "Oh dear!" Original "I Love Lucy" airer One of the networks. One of the networks Org. employing Diane Sawyer One of the TV networks Onetime network of 20-Across Original "I Love Lucy" airer Original "I Love Lucy" airer One of the major networks One of the major networks Onetime Paley net One of the major networks One of the major networks "Oh, dear" "Oh, woe!" Opposite of "Whoopee!" "Oh, my!" "Oy!" "Oh, dear!" Old-timey word of woe "Oh dear!" "Oh dear!" "Oh woe!" "Oh my!" "Oh, woe!" "Oh, no!" "Oh, dear!" "Oh gracious!" "Oh, my!" "Oh, no" Old-time word of woe Oral lament "Oh, woe!" "Oh, woe!" "Oy!" One way to carry a tune Ochone! O dear! Oh, dear me! Oh, me, oh, my! Oh me! Oh my! Old-time exclamation. Oh dear! Oh, dear. Oh, dear Oh, my! "Oh, dear" Ovid's "Eheu!" "O dear!" Oh, dear! "Oh me! Oh my!" "Oh, dear!" One way to carry a tune One way to carry a tune Only its Touch model is currently sold "Old MacDonald Had a Farm, ___" Old MacDonald's refrain