*The first one helped combat smallpox Crossword Clue

Here is the answer for the crossword clue *The first one helped combat smallpox . We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 7 letters. We think the likely answer to this clue is VACCINE.

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Crossword Answer For *The first one helped combat smallpox:

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40 Potential Answers:

RankAnswerLengthSourceDate
98% VACCINE *The first one helped combat smallpox (7)
3% ASSIST Help donkey first (6) (6) Puzzler Cryptic Jul 11, 2026
2% OFUSE Helpful to have (5) Newsday Aug 11, 2026
2% AIDS Helps (4) Universal Aug 9, 2026
2% SOS "Help!" (3) Universal Aug 9, 2026
2% ORC Battle of Helm's Deep combatant (3) LA Times Daily Aug 9, 2026
2% HINT Helpful suggestion (4) Commuter Aug 4, 2026
2% SPOTTER One helping with the heavy lifting? (7) Universal Aug 3, 2026
2% WAR Conscious after being shelled in combat (3) The Times Cryptic Aug 3, 2026
2% ASSISTANT One should help (9) (9) The Guardian Quick Jul 30, 2026
*The first one helped combat smallpox Crossword Clue
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We found 40 solutions for *The first one helped combat smallpox. The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is VACCINE.

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With our crossword solver search engine you have access to over 7 million clues. You can narrow down the possible answers by specifying the number of letters it contains. We found more than 40 answers for *The first one helped combat smallpox.