*With 45-Across, Iowa's most populous city Crossword Clue

Here is the answer for the crossword clue *With 45-Across, Iowa's most populous city . We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 3 letters. We think the likely answer to this clue is DES.

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Crossword Answer For *With 45-Across, Iowa's most populous city:

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40 Potential Answers:

RankAnswerLengthSourceDate
98% DES *With 45-Across, Iowa's most populous city (3)
77% SIOUX __ City, Iowa (5) LA Times Daily Jan 12, 2026
77% TOR Most populous city in Can. (3) LA Times Daily Dec 16, 2025
74% OSAKA Japan's third most populous city (5) Universal Feb 10, 2026
71% MST Its most populous city is Phoenix, Ariz. (3) The Atlantic Feb 12, 2026
71% NASHUA Second most populous city in New Hampshire (6) Universal Jan 25, 2026
71% AMES Iowa city (4) USA Today Quick Nov 12, 2025
71% E Iowa city (1) USA Today Quick Nov 12, 2025
69% ONTARIO Canada's most populous province (7)
69% BRUMMAGEM Local name for the UK's second most populous city (9) The Times Specialist Jan 5, 2026
*With 45-Across, Iowa's most populous city Crossword Clue
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We found 40 solutions for *With 45-Across, Iowa's most populous city. The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is DES.

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