Drug that reduces functional or nervous activity (10) Crossword Clue

Last Seen in:

Here is the answer for the crossword clue Drug that reduces functional or nervous activity (10) featured in Puzzler puzzle on December 26, 2025. We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 10 letters. We think the likely answer to this clue is DEPRESSANT.

Today's Mini Crossword

Like NYT Mini, but free. Forever. No playwall.

See results below advertisement

Crossword Answer For Drug that reduces functional or nervous activity (10):

You can click on thetiles to reveal letter by letter before uncovering the full solution.

advertisement

40 Potential Answers:

RankAnswerLengthSourceDate
98% DEPRESSANT Drug that reduces functional or nervous activity (10) (10) Puzzler Dec 26, 2025
92% DEPRESSANTS Drugs that reduce functional or nervous activity (11) (11)
6% TENSE Nervous (5) Commuter Dec 11, 2025
6% RELAXANT Drug reducing muscle strain (8) Premier Sunday Sep 28, 2025
5% USEDON Given to, as a drug (6) Wall Street Journal Dec 23, 2025
5% COLLYWOBBLES Nervous stomach (12) (12) The Guardian Quick Dec 19, 2025
5% BASH Fun function (4) LA Times Daily Dec 18, 2025
5% REUSE Reduce, __, recycle (5) Newsday Dec 18, 2025
5% LSD Microdosing drug (3) New York Times Dec 18, 2025
5% OPIATE Narcotic drug (6) The Telegraph Quick Dec 17, 2025

Clues for The Puzzler Puzzle on December 26, 2025

Drug that reduces functional or nervous activity (10) Crossword Clue
Stay up-to-date with our updates!
Explore your favorite daily puzzles and get quick tips, find missing answers to complete your crossword.
CW alt logo

Fresh Clues From Recent Puzzles

Your Crossword Clues FAQ Guide

We found 40 solutions for Drug that reduces functional or nervous activity (10). The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is DEPRESSANT.

With crossword-solver.io you will find 40 solutions. We use historic puzzles to find the best matches for your question. We add many new clues on a daily basis.

With our crossword solver search engine you have access to over 7 million clues. You can narrow down the possible answers by specifying the number of letters it contains. We found more than 40 answers for Drug that reduces functional or nervous activity (10).