Its last U.S. case was in 1949 Crossword Clue

Here is the answer for the crossword clue Its last U.S. case was in 1949 . We have found 41 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 8 letters. We think the likely answer to this clue is SMALLPOX.

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Crossword Answer For Its last U.S. case was in 1949:

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41 Potential Answers:

RankAnswerLengthSourceDate
98% SMALLPOX Its last U.S. case was in 1949 (8)
91% CHANT "U-S-A! U-S-A! …," e.g. (5) New York Times Jan 19, 2026
70% AMIMISTAKEN "Is it not the case?" (11) Universal Feb 1, 2026
70% LEST In case (4) LA Times Daily Jan 30, 2026
70% IFSO "In that case …" (4) New York Times Jan 20, 2026
70% TRENT "___'s Last Case" (5)
66% UNIT The "U" of CPU (4) LA Times Daily Feb 2, 2026
66% MAD "u ___, bro?" (3) The Atlantic Jan 23, 2026
66% ULTRA The "U" in UHF (5) New York Times Jan 6, 2026
66% HAUL U-____ (4) USA Today Quick Dec 3, 2025
Its last U.S. case was in 1949 Crossword Clue
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We found 41 solutions for Its last U.S. case was in 1949. The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is SMALLPOX.

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With our crossword solver search engine you have access to over 7 million clues. You can narrow down the possible answers by specifying the number of letters it contains. We found more than 41 answers for Its last U.S. case was in 1949.