Make a significant change Crossword Clue

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Here is the answer for the crossword clue Make a significant change last seen in Wall Street Journal puzzle. We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 6 letters. We think the likely answer to this clue is MUTATE.

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Crossword Answer For Make a significant change:

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40 Potential Answers:

RankAnswerLengthSourceDate
98% MUTATE Make a significant change (6) Wall Street Journal Apr 12, 2025
36% QUANTUMLEAPFROG Kermit making a significant change? (15)
4% ALTER Make changes to (5) Commuter Aug 27, 2025
4% AMENDS Makes changes to (6) USA Today Aug 5, 2025
3% KELCE Swift's significant other (5) Newsday Sep 5, 2025
3% ALTERED Changed (7) Wall Street Journal Sep 3, 2025
3% ALTERS Changes (6) The Telegraph Quick Sep 1, 2025
3% TURN Change of direction (4) Puzzler Backwords Aug 29, 2025
3% CENT Bit of change (4) LA Times Daily Aug 24, 2025
3% FATEFUL Having significant negative consequences (7) The Times Concise Aug 23, 2025

Last appeared together with the following clues in Wall Street Journal puzzle

Make a significant change Crossword Clue
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We found 40 solutions for Make a significant change. The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is MUTATE.

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