Make a significant change Crossword Clue

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Here is the answer for the crossword clue Make a significant change last seen in Wall Street Journal puzzle. We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 6 letters. We think the likely answer to this clue is MUTATE.

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Crossword Answer For Make a significant change:

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40 Potential Answers:

RankAnswerLengthSourceDate
98% MUTATE Make a significant change (6) Wall Street Journal Apr 12, 2025
35% QUANTUMLEAPFROG Kermit making a significant change? (15)
3% DYE It changes locks (3) The Telegraph Cross Atlantic Dec 19, 2025
3% KEEP "___ the change" (4) USA Today Dec 18, 2025
3% PITH Significance - ___ ball or helmet (4) (4) The Guardian Quick Dec 15, 2025
3% ONES Change for $5 (4) Newsday Dec 15, 2025
3% ADAPT Change to fit (5) Premier Sunday Dec 14, 2025
3% SUB Small change (3) Newsday Dec 13, 2025
3% CENT Not much change (4) Newsday Dec 13, 2025
3% MOVE Change places (4) LA Times Daily Dec 13, 2025

Last appeared together with the following clues in Wall Street Journal puzzle

Make a significant change Crossword Clue
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We found 40 solutions for Make a significant change. The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is MUTATE.

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