Make a significant change Crossword Clue

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Here is the answer for the crossword clue Make a significant change last seen in Wall Street Journal puzzle. We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 6 letters. We think the likely answer to this clue is MUTATE.

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Crossword Answer For Make a significant change:

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40 Potential Answers:

RankAnswerLengthSourceDate
98% MUTATE Make a significant change (6) Wall Street Journal Apr 12, 2025
35% QUANTUMLEAPFROG Kermit making a significant change? (15)
4% ALTER Make changes to (5) Newsday Apr 7, 2026
3% CENT Minimal change (4) Thomas Joseph May 16, 2026
3% COINS Small change (5) The Telegraph Quick May 15, 2026
3% ERA Significant stretch (3) The Telegraph Cross Atlantic May 13, 2026
3% FORMALISE Make official get in a queue when changing partners (9) The Telegraph Toughie May 13, 2026
3% IMPORTANCE Significance (10) (10) Mirror Classic May 12, 2026
3% ADAPT Adjust to change (5) Newsday May 11, 2026
3% KEEP "__ the change" (4) LA Times Daily May 5, 2026

Last appeared together with the following clues in Wall Street Journal puzzle

Make a significant change Crossword Clue
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We found 40 solutions for Make a significant change. The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is MUTATE.

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