Significant suffering Crossword Clue

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Here is the answer for the crossword clue Significant suffering last seen in Wall Street Journal puzzle. We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 5 letters. We think the likely answer to this clue is AGONY.

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Crossword Answer For Significant suffering:

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40 Potential Answers:

RankAnswerLengthSourceDate
98% AGONY Significant suffering (5) Wall Street Journal Jun 23, 2018
3% REDLETTERDAY Happy and significant occasion (3-6,3) (12) The Guardian Quick Oct 7, 2025
3% IMPORT Significance (6) LA Times Daily Oct 3, 2025
3% NOTEWORTHY Interesting or significant (10) (10) Mirror Classic Oct 3, 2025
3% PASSUS Pace having suffered? (6) The Times O Tempora Sep 27, 2025
3% MINUTEST Least significant flash on street (8) The Telegraph Cryptic Sep 25, 2025
3% ILL Suffering (3) Thomas Joseph Sep 23, 2025
3% AIL Suffer (3) LA Times Daily Sep 21, 2025
3% EMPHASIS Special importance or significance (8) (8) Mirror Classic Sep 21, 2025
3% MOAN Suffering sound (4) Wall Street Journal Sep 20, 2025

Last appeared together with the following clues in Wall Street Journal puzzle

Significant suffering Crossword Clue
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We found 40 solutions for Significant suffering. The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is AGONY.

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