Spanish explorer and conquistador who in 1541 became the first European to cross the Mississippi River (8) Crossword Clue

Here is the answer for the crossword clue Spanish explorer and conquistador who in 1541 became the first European to cross the Mississippi River (8) . We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 8 letters. We think the likely answer to this clue is HERNANDO.

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Crossword Answer For Spanish explorer and conquistador who in 1541 became the first European to cross the Mississippi River (8):

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40 Potential Answers:

RankAnswerLengthSourceDate
98% HERNANDO Spanish explorer and conquistador who in 1541 became the first European to cross the Mississippi River (8) (8)
6% HERNANDO DE SOTO Spanish explorer, the first documented European to cross the Mississippi River (16) The Times Specialist Sunday Dec 19, 2021
6% HERNANDODESOTO Spanish explorer, the first European documented as crossing the Mississippi (14) The Times Specialist Sunday Aug 25, 2019
5% PIZARRO Francisco -, Spanish conqueror of the Inca Empire who died in 1541 (7) (7) Mirror Quiz Nov 22, 2025
5% YAZOO River of Mississippi (5) Thomas Joseph Nov 15, 2025
5% ITASCA Lake that feeds the Mississippi River (6) LA Times Daily Nov 5, 2025
5% LASALLE Mississippi River explorer (7) Newsday Jun 23, 2024
5% DESOTO Mississippi River discoverer of 1541 (6)
4% LEIF First name in Norse exploration (4) New York Times Dec 6, 2025
4% FADED Became dim (5) Puzzler Backwords Dec 2, 2025
Spanish explorer and conquistador who in 1541 became the first European to cross the Mississippi River (8) Crossword Clue
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We found 40 solutions for Spanish explorer and conquistador who in 1541 became the first European to cross the Mississippi River (8). The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is HERNANDO.

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