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Substance in the middle of the 49-Across Crossword Clue
Here is the answer for the crossword clue Substance in the middle of the 49-Across . We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 5 letters. We think the likely answer to this clue is WATER.
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Crossword Answer For Substance in the middle of the 49-Across:
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40 Potential Answers:
| Rank | Answer | Length | Source | Date |
|---|---|---|---|---|
| 98% | WATER Substance in the middle of the 49-Across | (5) | ||
| 3% | DEMI Moore of "The Substance" | (4) | LA Times Daily | Sep 6, 2026 |
| 3% | OCARDS Pocket rockets, e.g., found in a 49-Across | (6) | New York Times | Sep 3, 2026 |
| 3% | MUSICNOTES Score symbols, or a description of 17-, 24-, 39-, and 49-Across | (10) | LA Times Daily | Sep 3, 2026 |
| 3% | LYES Caustic substances | (4) | Universal | Sep 1, 2026 |
| 3% | ERS 49 follower | (3) | Newsday | Aug 27, 2026 |
| 3% | RESIN Sticky substance | (5) | USA Today | Aug 24, 2026 |
| 3% | GLUE Sticky substance | (4) | Universal | Aug 23, 2026 |
| 3% | CORAL Reef substance | (5) | Puzzler Backwords | Aug 22, 2026 |
| 3% | CENTRE Middle | (6) | The Telegraph Quick | Aug 18, 2026 |
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We found 40 solutions for Substance in the middle of the 49-Across. The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is WATER.
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