Substance with sedative properties (6) Crossword Clue

Here is the answer for the crossword clue Substance with sedative properties (6) featured in Guardian Quick puzzle on December 16, 2025. We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 6 letters. We think the likely answer to this clue is OPIATE.

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Crossword Answer For Substance with sedative properties (6):

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40 Potential Answers:

RankAnswerLengthSourceDate
98% OPIATE Substance with sedative properties (6) (6) The Guardian Quick Dec 16, 2025
7% LANDED Propertied (6) The Telegraph Quick Dec 7, 2025
7% OPIOID Sedative substance (6)
6% LEASE Property contract (5) The Times Sunday Concise Dec 14, 2025
6% RATES Property taxes (5) The Times Concise Dec 13, 2025
6% LIEN Claim on a property (4) USA Today Dec 10, 2025
6% SALVE Soothing substance (5) USA Today Dec 5, 2025
6% ARSON Deliberate burning of property (5) The Telegraph Cross Atlantic Dec 4, 2025
6% SERUM Immunisation substance (5) (5) Puzzler Dec 4, 2025
6% NONMONETARYASSET Property or patents, to CPAs (16) Newsday Nov 30, 2025

Clues for The Guardian Quick Puzzle on December 16, 2025

Substance with sedative properties (6) Crossword Clue
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We found 40 solutions for Substance with sedative properties (6). The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is OPIATE.

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