What makes up a significant proportion of the universe is distressing subject (4,6) Crossword Clue

Here is the answer for the crossword clue What makes up a significant proportion of the universe is distressing subject (4,6) last seen in Guardian Quick Cryptic puzzle. We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 10 letters. We think the likely answer to this clue is DARKMATTER.

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Crossword Answer For What makes up a significant proportion of the universe is distressing subject (4,6):

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40 Potential Answers:

RankAnswerLengthSourceDate
98% DARKMATTER What makes up a significant proportion of the universe is distressing subject (4,6) (10) The Guardian Quick Cryptic Oct 4, 2025
6% MATTERED Subject facing journalist was of significance (8) The Telegraph Cryptic Oct 16, 2025
5% SKY What's up? (3) Wall Street Journal Oct 13, 2025
5% ACADEMIA The universe of universities (8) Premier Sunday Oct 12, 2025
5% MAYDAY Distress signal (6) The Telegraph Cross Atlantic Oct 9, 2025
5% EPIC Of heroic proportions (4) (4) Mirror Classic Oct 8, 2025
5% ANGST Adolescent's distress (5) Universal Oct 6, 2025
5% DOC "What's up, ___?" (3) New York Times Oct 5, 2025
5% IMPORT Significance (6) LA Times Daily Oct 3, 2025
5% MILESTONE I'm standing up in case somebody makes significant point (9) The Times Cryptic Sep 24, 2025

Last appeared together with the following clues in Guardian Quick Cryptic puzzle

What makes up a significant proportion of the universe is distressing subject (4,6) Crossword Clue
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We found 40 solutions for What makes up a significant proportion of the universe is distressing subject (4,6). The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is DARKMATTER.

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