"What's up with ___?" Crossword Clue

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Here is the answer for the crossword clue "What's up with ___?" last seen in Universal puzzle. We have found 41 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 4 letters. We think the likely answer to this clue is THAT.

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Crossword Answer For "What's up with ___?":

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41 Potential Answers:

RankAnswerLengthSourceDate
98% THAT "What's up with ___?" (4) Universal Feb 12, 2023
95% HIALL "What's up, everyone!" (5) USA Today Mar 22, 2026
95% HOWRU Texter's "What's up?" (5) LA Times Mini Mar 4, 2026
90% OKAY What a thumbs up means (4)
85% DOC "What's up, ___?" (Bugs Bunny's question) (3)
85% FROYO What L.A.'s Bigg Chill sells (5) Newsday Mar 21, 2026
80% GRANT Ulysses S. __ (5) Commuter Apr 1, 2026
80% LINT What some handheld devices pick up (4) Newsday Mar 28, 2026
80% HONEST On the up and up (6) Thomas Joseph Mar 20, 2026
80% ELSE "What ___ is there?" (4) The Atlantic Mar 15, 2026

Last appeared together with the following clues in Universal puzzle

"What's up with ___?" Crossword Clue
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We found 41 solutions for "What's up with ___?". The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is THAT.

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With our crossword solver search engine you have access to over 7 million clues. You can narrow down the possible answers by specifying the number of letters it contains. We found more than 41 answers for "What's up with ___?".