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*The first one helped combat smallpox Crossword Clue
Here is the answer for the crossword clue *The first one helped combat smallpox . We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 7 letters. We think the likely answer to this clue is VACCINE.
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Crossword Answer For *The first one helped combat smallpox:
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40 Potential Answers:
| Rank | Answer | Length | Source | Date |
|---|---|---|---|---|
| 98% | VACCINE *The first one helped combat smallpox | (7) | ||
| 3% | AID First ___ (immediate medical help) | (3) | ||
| 3% | VARIOLA Technical term for smallpox | (7) | The Telegraph Cross Atlantic | Dec 22, 2025 |
| 2% | USELESS Of no help | (7) | New York Times | Mar 30, 2026 |
| 2% | WON Emptied one's hand first, in Uno | (3) | Universal | Mar 26, 2026 |
| 2% | MMA Hybrid combat sport: Abbr. | (3) | ||
| 2% | HINT Help for a guesser | (4) | New York Times | Mar 24, 2026 |
| 2% | INITIAL First one egg, one with endless salt | (7) | The Telegraph Cryptic | Mar 23, 2026 |
| 2% | TIP Helpful hint | (3) | New York Times | Mar 23, 2026 |
| 2% | OPERATION Organiser's first physical exercise helping running | (9) | The Times Quick Cryptic | Mar 17, 2026 |
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We found 40 solutions for *The first one helped combat smallpox. The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is VACCINE.
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