A powerful drug obliterating pain, in use maybe from the beginning (5) Crossword Clue

Here is the answer for the crossword clue A powerful drug obliterating pain, in use maybe from the beginning (5) . We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 5 letters. We think the likely answer to this clue is OPIUM.

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Crossword Answer For A powerful drug obliterating pain, in use maybe from the beginning (5):

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40 Potential Answers:

RankAnswerLengthSourceDate
98% OPIUM A powerful drug obliterating pain, in use maybe from the beginning (5) (5)
6% ANEW From the beginning (4) Universal Jan 2, 2026
6% NARC US drugs investigator (4) The Telegraph Cross Atlantic Dec 23, 2025
6% DENOVO From the beginning (6) LA Times Daily Dec 19, 2025
6% ERADICATES Obliterates (10) (10) Mirror Classic Nov 15, 2025
6% DEMEROL Pain-relieving drug (7) New York Times Oct 5, 2025
5% MIGHTY Powerful (6) Thomas Joseph Jan 13, 2026
5% USHER Escort papa away from drug dealer (5) The Times Quick Cryptic Jan 10, 2026
5% PEA Power and energy beginning to assist plant (3) The Times Quick Cryptic Jan 9, 2026
5% ONSET Beginning (5) The Telegraph Cross Atlantic Jan 8, 2026
A powerful drug obliterating pain, in use maybe from the beginning (5) Crossword Clue
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We found 40 solutions for A powerful drug obliterating pain, in use maybe from the beginning (5). The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is OPIUM.

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With our crossword solver search engine you have access to over 7 million clues. You can narrow down the possible answers by specifying the number of letters it contains. We found more than 40 answers for A powerful drug obliterating pain, in use maybe from the beginning (5).