Downer drug Crossword Clue

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Here is the answer for the crossword clue Downer drug last seen in Premier Sunday puzzle. We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 6 letters. We think the likely answer to this clue is OPIATE.

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Crossword Answer For Downer drug:

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40 Potential Answers:

RankAnswerLengthSourceDate
98% OPIATE Downer drug (6) Premier Sunday Jun 16, 2024
98% OPIOID Downer drug (6) Premier Sunday Dec 15, 2019
37% TRANK Downer drug, slangily (5)
3% CRACKPOT Drug after drug - crazy (8) The Times Quick Cryptic Nov 29, 2025
3% AMBIEN Sleep aid drug (6) Eugene Sheffer Nov 24, 2025
3% OPIUM Poppy drug (5) Eugene Sheffer Nov 7, 2025
3% NARC Drug cop, informally (4)
3% ELI Lilly of drugs (3) Premier Sunday Nov 2, 2025
3% LSD Woodstock drug (3) Universal Nov 1, 2025
3% DISAPPOINTMENT Downer in loss of position? (14) The Telegraph Toughie Oct 21, 2025

Last appeared together with the following clues in Premier Sunday puzzle

Downer drug Crossword Clue
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We found 40 solutions for Downer drug. The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is OPIATE.

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With our crossword solver search engine you have access to over 7 million clues. You can narrow down the possible answers by specifying the number of letters it contains. We found more than 40 answers for Downer drug.