Downer drug Crossword Clue

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Here is the answer for the crossword clue Downer drug last seen in Premier Sunday puzzle. We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 6 letters. We think the likely answer to this clue is OPIATE.

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Crossword Answer For Downer drug:

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40 Potential Answers:

RankAnswerLengthSourceDate
98% OPIATE Downer drug (6) Premier Sunday Jun 16, 2024
98% OPIOID Downer drug (6) Premier Sunday Dec 15, 2019
37% TRANK Downer drug, slangily (5)
4% ANTIFUNGAL Drug supplied by Debbie Downer? (10)
3% DEMEROL Pain-relieving drug (7) New York Times Oct 5, 2025
3% LYRICA Fibromyalgia drug brand (6) Wall Street Journal Sep 29, 2025
3% ADDICT Habitual drug user (6) The Telegraph Quick Sep 24, 2025
3% LSD Trippy drug (3) LA Times Daily Sep 23, 2025
3% PHARMA Big ____, the drug industry (6) The Telegraph Cross Atlantic Sep 22, 2025
3% MEDS Drugs (4) The Telegraph Cross Atlantic Sep 14, 2025

Last appeared together with the following clues in Premier Sunday puzzle

Downer drug Crossword Clue
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We found 40 solutions for Downer drug. The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is OPIATE.

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With our crossword solver search engine you have access to over 7 million clues. You can narrow down the possible answers by specifying the number of letters it contains. We found more than 40 answers for Downer drug.