Highly significant Crossword Clue

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Here is the answer for the crossword clue Highly significant last seen in Newsday puzzle. We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 5 letters. We think the likely answer to this clue is MAJOR.

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Crossword Answer For Highly significant:

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4 Potential Answers:

AnswerLengthSourceDate
MAJOR Highly significant (5) Newsday Aug 28, 2022
EPOCHAL Highly significant (7) Newsday Dec 4, 2020
GREAT Highly significant (5)
HISTORIC Highly significant (8)

36 Similar Clues:

RankAnswerLengthSourceDate
31% QUANTUMLEAP Sudden highly significant advance (11)
3% ESTEEM Regard highly (6) USA Today Oct 20, 2026
3% MOST Highly (4) Newsday Oct 10, 2026
3% PILOTING Highly controlling? (8) New York Times Oct 2, 2026
3% LAUD Speak highly of (4) LA Times Daily Oct 2, 2026
3% ERRATIC Highly inconsistent (7) Commuter Sep 28, 2026
3% ADMIRE Think highly of (6) The Times Sunday Concise Sep 27, 2026
3% AGHAST Highly horrified (6) Newsday Sep 27, 2026
3% CULT Highly devoted group (4) New York Times Special Crossword Sep 23, 2026
3% ERA Significant period (3) Wall Street Journal Sep 21, 2026

Last appeared together with the following clues in Newsday puzzle

Highly significant Crossword Clue
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We found 40 solutions for Highly significant. The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is MAJOR.

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