Loses potency, like a painkiller Crossword Clue

Last Seen in:

Here is the answer for the crossword clue Loses potency, like a painkiller last seen in USA Today puzzle. We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 8 letters. We think the likely answer to this clue is WEARSOFF.

Today's Mini Crossword

Like NYT Mini, but free. Forever. No playwall.

See results below advertisement

Crossword Answer For Loses potency, like a painkiller:

You can click on thetiles to reveal letter by letter before uncovering the full solution.

advertisement

40 Potential Answers:

RankAnswerLengthSourceDate
98% WEARSOFF Loses potency, like a painkiller (8) USA Today Jan 6, 2017
6% CLOUT High potency (5) Newsday Jan 31, 2026
5% ANODYNE Painkiller annoyed stranger (7) (7) Puzzler Cryptic Mar 10, 2026
5% ACHE Reason to take a painkiller (4) New York Times Feb 25, 2026
5% SNAPS Loses it (5) Thomas Joseph Feb 14, 2026
5% ENDORPHINS Neurochemicals that act as natural painkillers (10) LA Times Daily Jan 21, 2026
4% PALE Lose color (4) New York Times Midi Mar 20, 2026
4% TRIPUP Lose one's footing (4,2) (6) The Guardian Quick Mar 19, 2026
4% SKID Lose traction (4) Newsday Mar 17, 2026
4% ATSTAKE To lose like Joan of Arc when she died (7) The Telegraph Toughie Mar 4, 2026

Last appeared together with the following clues in USA Today puzzle

Loses potency, like a painkiller Crossword Clue
Stay up-to-date with our updates!
Explore your favorite daily puzzles and get quick tips, find missing answers to complete your crossword.
CW alt logo

Fresh Clues From Recent Puzzles

Your Crossword Clues FAQ Guide

We found 40 solutions for Loses potency, like a painkiller. The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is WEARSOFF.

With crossword-solver.io you will find 40 solutions. We use historic puzzles to find the best matches for your question. We add many new clues on a daily basis.

With our crossword solver search engine you have access to over 7 million clues. You can narrow down the possible answers by specifying the number of letters it contains. We found more than 40 answers for Loses potency, like a painkiller.