Panama ___ (important trade route) Crossword Clue

Here is the answer for the crossword clue Panama ___ (important trade route) . We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 5 letters. We think the likely answer to this clue is CANAL.

Today's Mini Crossword

Like NYT Mini, but free. Forever. No playwall.

See results below advertisement

Crossword Answer For Panama ___ (important trade route):

You can click on thetiles to reveal letter by letter before uncovering the full solution.

advertisement

40 Potential Answers:

RankAnswerLengthSourceDate
98% CANAL Panama ___ (important trade route) (5)
8% ARTERY Important route (6) New York Times Mar 26, 2026
6% WAY Route (3) Universal Apr 22, 2026
6% DEFEAT Rout (6) The Telegraph Quick Mar 16, 2026
5% RINGROAD Circular route (8) The Telegraph Quick Apr 30, 2026
5% VITAL Of the utmost importance (5) Commuter Apr 30, 2026
5% ERA Important age (3) Thomas Joseph Apr 30, 2026
5% OFFS Trade-__: compromises (4) LA Times Daily Apr 23, 2026
5% CHIEF Most important (5) Newsday Apr 23, 2026
5% KAYO Bout rout (4) New York Times Apr 14, 2026
Panama ___ (important trade route) Crossword Clue
Stay up-to-date with our updates!
Explore your favorite daily puzzles and get quick tips, find missing answers to complete your crossword.
CW alt logo

Fresh Clues From Recent Puzzles

Your Crossword Clues FAQ Guide

We found 40 solutions for Panama ___ (important trade route). The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is CANAL.

With crossword-solver.io you will find 40 solutions. We use historic puzzles to find the best matches for your question. We add many new clues on a daily basis.

With our crossword solver search engine you have access to over 7 million clues. You can narrow down the possible answers by specifying the number of letters it contains. We found more than 40 answers for Panama ___ (important trade route).