Professor who is Sherlock Holmes's main antagonist (8) Crossword Clue

Here is the answer for the crossword clue Professor who is Sherlock Holmes's main antagonist (8) . We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 8 letters. We think the likely answer to this clue is MORIARTY.

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Crossword Answer For Professor who is Sherlock Holmes's main antagonist (8):

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40 Potential Answers:

RankAnswerLengthSourceDate
98% MORIARTY Professor who is Sherlock Holmes's main antagonist (8) (8)
81% DEERSTALKER Sherlock Holmes' hat (11) Commuter Sep 3, 2025
81% IRENE Adler who outsmarted Sherlock Holmes (5) The Telegraph Cross Atlantic Aug 2, 2025
75% AFOOT "The game is ___" (Sherlock Holmes line) (5)
75% WATSON Sherlock Holmes' confidant (6)
72% ENOLA ___ Holmes (Sherlock's sister, on Netflix) (5) New York Times Jul 21, 2025
69% DRWATSON Sherlock Holmes' sidekick (2,6) (8)
69% HANSOM Type of cab for Sherlock Holmes (6) Universal Jun 2, 2025
67% BASIL ___ Rathbone: Actor who portrayed Sherlock Holmes (5) (5)
64% ELEMENTARY US take on the Sherlock Holmes story (10)
Professor who is Sherlock Holmes's main antagonist (8) Crossword Clue
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We found 40 solutions for Professor who is Sherlock Holmes's main antagonist (8). The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is MORIARTY.

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With our crossword solver search engine you have access to over 7 million clues. You can narrow down the possible answers by specifying the number of letters it contains. We found more than 40 answers for Professor who is Sherlock Holmes's main antagonist (8).