Professor who is Sherlock Holmes's main antagonist (8) Crossword Clue

Here is the answer for the crossword clue Professor who is Sherlock Holmes's main antagonist (8) . We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 8 letters. We think the likely answer to this clue is MORIARTY.

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Crossword Answer For Professor who is Sherlock Holmes's main antagonist (8):

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40 Potential Answers:

RankAnswerLengthSourceDate
98% MORIARTY Professor who is Sherlock Holmes's main antagonist (8) (8)
78% DEERSTALKER Sherlock Holmes' hat (11) Commuter Sep 3, 2025
75% IRENE Adler who outsmarted Sherlock Holmes (5) The Telegraph Cross Atlantic Aug 2, 2025
69% BRETT Jeremy ____'s most famous acting role was Sherlock Holmes (5) The Times Specialist Sunday Nov 23, 2025
69% NATE Main antagonist on HBO's "Euphoria" (4) New York Times Oct 19, 2025
69% AFOOT "The game is ___" (Sherlock Holmes line) (5)
64% ZUCCO George -, Manchester-born actor who played Professor Moriarty in 1939 film drama The Adventures of Sherlock Holmes (5) (5) Mirror Quiz Nov 20, 2025
64% BUSTS The Napoleons in the Sherlock Holmes story "The Adventure of the Six Napoleons" (5) Wall Street Journal Oct 25, 2025
58% BELLIGERENT Antagonistic (11) (11) Puzzler Nov 21, 2025
58% IAGO "Othello" antagonist (4) USA Today Nov 8, 2025
Professor who is Sherlock Holmes's main antagonist (8) Crossword Clue
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We found 40 solutions for Professor who is Sherlock Holmes's main antagonist (8). The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is MORIARTY.

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With our crossword solver search engine you have access to over 7 million clues. You can narrow down the possible answers by specifying the number of letters it contains. We found more than 40 answers for Professor who is Sherlock Holmes's main antagonist (8).