Sedative substance Crossword Clue

Here is the answer for the crossword clue Sedative substance . We have found 40 possible answers for this clue in our database. Among them, one solution stands out with a 98% match which has a length of 6 letters. We think the likely answer to this clue is OPIOID.

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Crossword Answer For Sedative substance:

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40 Potential Answers:

RankAnswerLengthSourceDate
98% OPIOID Sedative substance (6)
4% OPIATE Substance with sedative properties (6) (6) The Guardian Quick Dec 16, 2025
3% OWNERSHIP Daughter's wiped out by sedatives in possession (9) The Times Cryptic Dec 19, 2025
3% GEL Hairstyling substance (3) Puzzler Backwords Dec 18, 2025
3% MEDICINE Pharmaceutical substance (8) The Times Concise Dec 17, 2025
3% OOZE Primordial substance (4) New York Times Dec 17, 2025
3% SALVE Soothing substance (5) USA Today Dec 5, 2025
3% SERUM Immunisation substance (5) (5) Puzzler Dec 4, 2025
3% MEATY Full of substance (5) Puzzler Backwords Nov 29, 2025
3% PAPER Substance for writing on (5) (5) Puzzler Nov 23, 2025
Sedative substance Crossword Clue
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We found 40 solutions for Sedative substance. The top solutions are determined by popularity, ratings and frequency of searches. The most likely answer for the clue is OPIOID.

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